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Immunodeficient mice are better for modeling the transfusion of human blood components than wild-type mice

Animal models are vital to the study of transfusion and development of new blood products. Post-transfusion recovery of human blood components can be studied in mice, however, there is a need to identify strains that can best tolerate xenogeneic transfusions, as well as to optimize such protocols. S...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Blessinger, Sophia A., Tran, Johnson Q., Jackman, Rachael P., Gilfanova, Renata, Rittenhouse, Jacqueline, Gutierrez, Alan G., Heitman, John W., Hazegh, Kelsey, Kanias, Tamir, Muench, Marcus O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394438/
https://ncbi.nlm.nih.gov/pubmed/32735605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237106
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