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Drug candidate identification based on gene expression of treated cells using tensor decomposition-based unsupervised feature extraction for large-scale data

BACKGROUND: Although in silico drug discovery is necessary for drug development, two major strategies, a structure-based and ligand-based approach, have not been completely successful. Currently, the third approach, inference of drug candidates from gene expression profiles obtained from the cells t...

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Zapisane w:
Opis bibliograficzny
Wydane w:BMC Bioinformatics
1. autor: Taguchi, Y-h.
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2019
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394334/
https://ncbi.nlm.nih.gov/pubmed/30717646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2395-8
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