miR-196b-5p-enriched extracellular vesicles from tubular epithelial cells mediated aldosterone-induced renal fibrosis in mice with diabetes

INTRODUCTION: Aldosterone is a mediator of progressive renal disease, but the mechanisms for aldosterone-mediated renal impairment in mice with diabetes are not fully defined. METHODS: Aldosterone and/or mineralocorticoid receptor antagonist eplerenone were used to treat the db/db mice with diabetes...

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Detalhes bibliográficos
Publicado no:BMJ Open Diabetes Res Care
Main Authors: Hu, Renzhi, Li, Xuan, Peng, Chuan, Gao, Ruifei, Ma, Linqiang, Hu, Jinbo, Luo, Ting, Qing, Hua, Wang, Yue, Ge, Qian, Wang, Zhihong, Wu, Chaodong, Xiao, Xiaoqiu, Yang, Jun, Young, Morag J, Li, Qifu, Yang, Shumin
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Pathophysiology/Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394302/
https://ncbi.nlm.nih.gov/pubmed/32727744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-001101
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