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The structural basis of T4 phage lysis control: DNA as the signal for lysis inhibition

Optimal phage propagation depends on the regulation of the lysis of the infected host cell. In T4 phage infection, lysis occurs when the holin protein (T) forms lesions in the host membrane. However, the lethal function of T can be blocked by an antiholin (RI) during lysis inhibition (LIN). LIN sets...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Krieger, Inna, Kuznetsov, Vladimir, Chang, Jeng-Yih, Zhang, Junjie, Moussa, Samir, Young, Ryland, Sacchettini, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394242/
https://ncbi.nlm.nih.gov/pubmed/32562709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.06.013
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