Agonist-Independent GPCR Activity Regulates Anterior-Posterior Targeting of Olfactory Sensory Neurons

G-protein coupled receptors (GPCRs) are known to possess two different conformations, active and inactive, and spontaneously alternate between the two in the absence of ligands. Here, we analyzed the agonist-independent GPCR activity for its possible role in receptor-instructed axonal projection. We...

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Vydáno v:Cell
Hlavní autoři: Nakashima, Ai, Takeuchi, Haruki, Imai, Takeshi, Saito, Harumi, Kiyonari, Hiroshi, Abe, Takaya, Chen, Min, Weinstein, Lee S., Yu, C. Ron, Storm, Daniel R., Nishizumi, Hirofumi, Sakano, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394037/
https://ncbi.nlm.nih.gov/pubmed/24034253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.033
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