Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of multiple sclerosis (MS), a neuroinflammatory and demyelinating disease characterized by multifocal perivascular infiltrates of immune cells. Although EAE is predominantly considered a T helper 1-driven aut...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Ferrara, Giovanni, Benzi, Andrea, Sturla, Laura, Marubbi, Daniela, Frumento, Davide, Spinelli, Sonia, Abbotto, Elena, Ivaldi, Federico, von Holtey, Maria, Murone, Maximilien, Nencioni, Alessio, Uccelli, Antonio, Bruzzone, Santina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393881/
https://ncbi.nlm.nih.gov/pubmed/32736564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01906-1
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