Direct lineage tracing reveals Activin-a potential for improved pancreatic homing of bone marrow mesenchymal stem cells and efficient ß-cell regeneration in vivo

BACKGROUND: Despite the potential, bone marrow-derived mesenchymal stem cells (BMSCs) show limitations for beta (ß)-cell replacement therapy due to inefficient methods to deliver BMSCs into pancreatic lineage. In this study, we report TGF-ß family member protein, Activin-a potential to stimulate eff...

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Detalles Bibliográficos
Publicado en:Stem Cell Res Ther
Main Authors: Dadheech, Nidheesh, Srivastava, Abhay, Vakani, Mitul, Shrimali, Paresh, Bhonde, Ramesh, Gupta, Sarita
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393856/
https://ncbi.nlm.nih.gov/pubmed/32731883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01843-z
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