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Lung-protective ventilation suppresses systemic and hepatic vein levels of cell-free DNA in porcine experimental post-operative sepsis

BACKGROUND: Plasma levels of cell-free DNA (cf-DNA) are known to be elevated in sepsis and high levels are associated with a poor prognosis. Mechanical ventilation affects systemic inflammation in which lung-protective ventilation attenuates the inflammatory response. The aim was to study the effect...

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Pubblicato in:BMC Pulm Med
Autori principali: Nyberg, Axel, Larsson, Alexander, Jylhävä, Juulia, Hurme, Mikko, Sperber, Jesper, Lipcsey, Miklós, Castegren, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393331/
https://ncbi.nlm.nih.gov/pubmed/32736620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-020-01239-y
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