Effect of selective I (K,ACh) inhibition by XAF‐1407 in an equine model of tachypacing‐induced persistent atrial fibrillation

BACKGROUND AND PURPOSE: Inhibition of the G‐protein gated ACh‐activated inward rectifier potassium current, I (K,ACh) may be an effective atrial selective treatment strategy for atrial fibrillation (AF). Therefore, the anti‐arrhythmic and electrophysiological properties of a novel putatively potent...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Fenner, Merle Friederike, Carstensen, Helena, Dalgas Nissen, Sarah, Melis Hesselkilde, Eva, Scott Lunddahl, Christine, Adler Hess Jensen, Maja, Loft‐Andersen, Ameli Victoria, Sattler, Stefan Michael, Platonov, Pyotr, El‐Haou, Said, Jackson, Claire, Tang, Raymond, Kirby, Robert, Ford, John, Schotten, Ulrich, Milnes, James, Svane Sørensen, Ulrik, Jespersen, Thomas, Buhl, Rikke
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393200/
https://ncbi.nlm.nih.gov/pubmed/32436234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15100
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