Effect of selective I (K,ACh) inhibition by XAF‐1407 in an equine model of tachypacing‐induced persistent atrial fibrillation

BACKGROUND AND PURPOSE: Inhibition of the G‐protein gated ACh‐activated inward rectifier potassium current, I (K,ACh) may be an effective atrial selective treatment strategy for atrial fibrillation (AF). Therefore, the anti‐arrhythmic and electrophysiological properties of a novel putatively potent...

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書誌詳細
出版年:Br J Pharmacol
主要な著者: Fenner, Merle Friederike, Carstensen, Helena, Dalgas Nissen, Sarah, Melis Hesselkilde, Eva, Scott Lunddahl, Christine, Adler Hess Jensen, Maja, Loft‐Andersen, Ameli Victoria, Sattler, Stefan Michael, Platonov, Pyotr, El‐Haou, Said, Jackson, Claire, Tang, Raymond, Kirby, Robert, Ford, John, Schotten, Ulrich, Milnes, James, Svane Sørensen, Ulrik, Jespersen, Thomas, Buhl, Rikke
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393200/
https://ncbi.nlm.nih.gov/pubmed/32436234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15100
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