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Restoration of HDAC2 and Nrf2 by andrographolide overcomes corticosteroid resistance in chronic obstructive pulmonary disease

BACKGROUND AND PURPOSE: Corticosteroid resistance poses a major barrier to an effective anti‐inflammatory therapy for chronic obstructive pulmonary disease (COPD). The present study aimed to investigate potential corticosteroid re‐sensitization actions of andrographolide, a bioactive molecule from t...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Liao, Wupeng, Lim, Albert Y. H., Tan, W. S. Daniel, Abisheganaden, John, Wong, W. S. Fred
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393195/
https://ncbi.nlm.nih.gov/pubmed/32335896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15080
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