Paraventricular hypothalamus mediates diurnal rhythm of metabolism

Defective rhythmic metabolism is associated with high-fat high-caloric diet (HFD) feeding, ageing and obesity; however, the neural basis underlying HFD effects on diurnal metabolism remains elusive. Here we show that deletion of BMAL1, a core clock gene, in paraventricular hypothalamic (PVH) neurons...

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Pubblicato in:Nat Commun
Autori principali: Kim, Eun Ran, Xu, Yuanzhong, Cassidy, Ryan M., Lu, Yungang, Yang, Yongjie, Tian, Jinbin, Li, De-Pei, Van Drunen, Rachel, Ribas-Latre, Aleix, Cai, Zhao-Lin, Xue, Mingshan, Arenkiel, Benjamin R., Eckel-Mahan, Kristin, Xu, Yong, Tong, Qingchun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393104/
https://ncbi.nlm.nih.gov/pubmed/32732906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17578-7
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