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Functional fine-mapping of noncoding risk variants in amyotrophic lateral sclerosis utilizing convolutional neural network

Recent large-scale genome-wide association studies have identified common genetic variations that may contribute to the risk of amyotrophic lateral sclerosis (ALS). However, pinpointing the risk variants in noncoding regions and underlying biological mechanisms remains a major challenge. Here, we co...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Yousefian-Jazi, Ali, Sung, Min Kyung, Lee, Taeyeop, Hong, Yoon-Ho, Choi, Jung Kyoon, Choi, Jinwook
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393092/
https://ncbi.nlm.nih.gov/pubmed/32732921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69790-6
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