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Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles
BACKGROUND: Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer’s disease (AD). Recent evidence has suggested that packaging and secretion of APP and its amyloidogenic cleaved products into smal...
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| Pubblicato in: | BMC Mol Cell Biol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7392838/ https://ncbi.nlm.nih.gov/pubmed/32731849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00302-0 |
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