Integrated bioinformatics analysis to decipher molecular mechanism of compound Kushen injection for esophageal cancer by combining WGCNA with network pharmacology

Compound Kushen injection (CKI), a medicine in widespread clinical use in China, has proven therapeutic effects on cancer. However, few molecular mechanism analyses have been carried out. To address this problem, bioinformatics approaches combining weighted gene co-expression network analysis with n...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhou, Wei, Wu, Jiarui, Zhang, Jingyuan, Liu, Xinkui, Guo, Siyu, Jia, ShanShan, Zhang, Xiaomeng, Zhu, Yingli, Wang, Miaomiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391752/
https://ncbi.nlm.nih.gov/pubmed/32728182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69708-2
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