Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies

The overexpression of immunomarker programmed cell death protein 1 (PD-1) and engagement of PD-1 to its ligand, PD-L1, are involved in the functional impairment of cluster of differentiation 8(+) (CD8(+)) T cells, contributing to cancer progression. However, heterogeneities in PD-L1 expression and v...

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Veröffentlicht in:ACS Nano
Hauptverfasser: Ou, Yu-Chuan, Wen, Xiaona, Johnson, Christopher A., Shae, Daniel, Ayala, Oscar D., Webb, Joseph A., Lin, Eugene C., DeLapp, Rossane C., Boyd, Kelli L., Richmond, Ann, Mahadevan-Jansen, Anita, Rafat, Marjan, Wilson, John T., Balko, Justin M., Tantawy, Mohammed N., Vilgelm, Anna E., Bardhan, Rizia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391408/
https://ncbi.nlm.nih.gov/pubmed/31851488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b07326
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