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Valeriana officinalis Counteracts Rotenone Effects on Spreading Depression in the Rat Brain in vivo and Protects Against Rotenone Cytotoxicity Toward Rat Glioma C6 Cells in vitro

Astrocytes can protect neurons against oxidative stress and excitability-dependent disorders, such as epilepsy. Valeriana officinalis has been used as anticonvulsant and can exert an antioxidant effect, which may underlie its opposing action against the toxic effects of the pesticide rotenone. We in...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Amaral de Brito, Ana Paula, Galvão de Melo, Isabel Michely da Silva, El-Bachá, Ramon Santos, Guedes, Rubem Carlos Araújo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390944/
https://ncbi.nlm.nih.gov/pubmed/32792901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00759
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