Enhanced hyaluronan signaling and autophagy dysfunction by VPS35 D620N

The motor features of Parkinson’s disease (PD) result from the loss of dopaminergic (DA) neurons in the substantia nigra with autophagy dysfunction being closely linked to this disease. A PD-causing familial mutation in VPS35 (D620N) has been reported to inhibit autophagy. In order to identify signa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuroscience
Prif Awduron: Rahman, Abir A., Soto-Avellaneda, Alejandro, Jin, Hyun Yong, Stojkovska, Iva, Lai, Nathan K., Albright, Joshua E., Webb, Abby R., Oe, Emily, Valarde, Jacob P., Oxford, Alexandra E., Urquhart, Paige E., Wagner, Brandon, Brown, Connor, Amado, Isabella, Vasquez, Peyton, Lehning, Nicholas, Grozdanov, Veselin, Pu, Xinzhu, Danzer, Karin M., Morrison, Brad E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390708/
https://ncbi.nlm.nih.gov/pubmed/32540366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.06.009
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