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Characterization of Regulatory T cell Expansion for Manufacturing Cellular Immunotherapies

Regulatory T cells (T(regs)) are critical mediators of peripheral immune tolerance. T(regs) suppress immune activation against self-antigens and are the focus of cell-based therapies for autoimmune diseases. However, T(regs) circulate at a very low frequency in blood, limiting the number of cells th...

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Vydáno v:Biomater Sci
Hlavní autoři: McBride, David A., Kerr, Matthew D., Wai, Shinya L., Yee, Yvonne Y., Ogbonna, Dora A., Shah, Nisarg J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390695/
https://ncbi.nlm.nih.gov/pubmed/32441280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0bm00622j
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