Age-induced NLRP3 Inflammasome Over-activation Increases Lethality of SARS-CoV-2 Pneumonia in Elderly Patients

Age is one of the most important prognostic factors associated to lethality in SARS-CoV-2 infection. In multivariate analysis, advanced age was an independent risk factor for death. Recent studies suggest a role for the nucleotide-binding domain and leucine rich repeat containing family, pyrin domai...

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Vydáno v:Aging Dis
Hlavní autoři: Lara, Pedro C, Macías-Verde, David, Burgos-Burgos, Javier
Médium: Artigo
Jazyk:Inglês
Vydáno: JKL International LLC 2020
Témata:
Opinion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390513/
https://ncbi.nlm.nih.gov/pubmed/32765942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2020.0601
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