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溴化结构域蛋白抑制剂JQ1对哮喘小鼠气道重塑作用机制研究

OBJECTIVE: To investigate the molecular mechanism of action of BET bromodomain inhibitor JQ1 in treating airway remodeling in asthmatic mice. METHODS: A total of 24 mice were randomly divided into control group, ovalbumin (OVA)-induced asthma group (OVA group), and JQ1 intervention group (JQ1+OVA gr...

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Publicado en:Zhongguo Dang Dai Er Ke Za Zhi
Formato: Artigo
Idioma:Inglês
Publicado: 中国当代儿科杂志编辑部 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7389801/
https://ncbi.nlm.nih.gov/pubmed/29237530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7499/j.issn.1008-8830.2017.12.011
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