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Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds

OBJECTIVES: The search for new TB drugs has become one of the great challenges for modern medicinal chemistry. An improvement in the outcomes of TB chemotherapy can be achieved by the development of new, shorter, cheap, safe and effective anti-TB regimens. METHODS: Chalcones (1a-1o) were synthesized...

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Detalhes bibliográficos
Publicado no:Cell Surf
Main Authors: Anagani, B., Singh, J., Bassin, J.P., Besra, G.S., Benham, C., Reddy, T.R.K., Cox, J.A.G., Goyal, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388970/
https://ncbi.nlm.nih.gov/pubmed/32743153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcsw.2020.100041
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