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Prazosin inhibits the proliferation, migration and invasion, but promotes the apoptosis of U251 and U87 cells via the PI3K/AKT/mTOR signaling pathway

Prazosin, an α-adrenergic receptor antagonist, is used to treat mild to moderate hypertension. It has recently been discovered that α-adrenergic receptors may have potential antitumor properties. Therefore, in the present study, the effect of prazosin on human glioblastoma and the underlying mechani...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: Zhang, Jing, Fan, Jiye
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388556/
https://ncbi.nlm.nih.gov/pubmed/32765662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8772
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