Carboxyamidotriazole exerts anti-inflammatory activity in lipopolysaccharide-induced RAW264.7 macrophages by inhibiting NF-κB and MAPKs pathways

Carboxyamidotriazole (CAI), originally developed as a non-cytotoxic anti-cancer drug, was shown to have anti-inflammatory activity according to recent studies in a number of animal models of inflammation. However, its mechanism of action has not been characterized. Therefore, the present study was p...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Lu, Shan, Duan, Mengyuan, Guo, Zehao, Zhou, Yongting, Wu, Danwei, Zhang, Xiaojuan, Wang, Yicheng, Ye, Caiying, Ju, Rui, Li, Juan, Zhang, Dechang, Zhu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388320/
https://ncbi.nlm.nih.gov/pubmed/32742379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8889
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