Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

IMPORTANCE: There are limitations in current diagnostic testing approaches for Alzheimer disease (AD). OBJECTIVE: To examine plasma tau phosphorylated at threonine 217 (P-tau217) as a diagnostic biomarker for AD. DESIGN, SETTING, AND PARTICIPANTS: Three cross-sectional cohorts: an Arizona-based neur...

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Vydáno v:JAMA
Hlavní autoři: Palmqvist, Sebastian, Janelidze, Shorena, Quiroz, Yakeel T., Zetterberg, Henrik, Lopera, Francisco, Stomrud, Erik, Su, Yi, Chen, Yinghua, Serrano, Geidy E., Leuzy, Antoine, Mattsson-Carlgren, Niklas, Strandberg, Olof, Smith, Ruben, Villegas, Andres, Sepulveda-Falla, Diego, Chai, Xiyun, Proctor, Nicholas K., Beach, Thomas G., Blennow, Kaj, Dage, Jeffrey L., Reiman, Eric M., Hansson, Oskar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2020
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388060/
https://ncbi.nlm.nih.gov/pubmed/32722745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.12134
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