Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment

Immune checkpoint inhibitors (ICIs) targeting immune checkpoint proteins, such as CTLA-4 and PD-1/PD-L1, have demonstrated remarkable and durable clinical responses in various cancer types. However, a considerable number of patients receiving ICIs eventually experience a relapse due to diverse resis...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Jiang, Zhou, Hsu, Jennifer L., Li, Yintao, Hortobagyi, Gabriel N., Hung, Mien-Chie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387712/
https://ncbi.nlm.nih.gov/pubmed/32775303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01197
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