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Replication of the Association Between Keratoconus and Polymorphisms in PNPLA2 and MAML2 in a Han Chinese Population

Keratoconus (KC) is a complex ocular disease that is affected by both genetic and non-genetic triggers. A recent genome-wide association study (GWAS) identified a genome-wide significant locus for KC in the region of PNPLA2 (rs61876744), as well as a suggestive signal in the MAML2 (rs10831500) locus...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Zhang, Jing, Li, Yue, Dai, Yiqin, Xu, Jianjiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387689/
https://ncbi.nlm.nih.gov/pubmed/32793291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00827
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