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BDNF belongs to the nurse-like cell secretome and supports survival of B chronic lymphocytic leukemia cells

Evading apoptosis and sustained survival signaling pathways are two central hallmarks of B-cell chronic lymphocytic leukemia (B-CLL) cells. In this regard, nurse-like cells (NLC), the monocyte-derived type 2 macrophages, deliver stimulatory signals via B-cell activating factor (BAFF), a proliferatio...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Talbot, Hugo, Saada, Sofiane, Barthout, Elodie, Gallet, Paul-François, Gachard, Nathalie, Abraham, Julie, Jaccard, Arnaud, Troutaud, Danielle, Lalloué, Fabrice, Naves, Thomas, Fauchais, Anne-Laure, Jauberteau, Marie-Odile
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387561/
https://ncbi.nlm.nih.gov/pubmed/32724091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69307-1
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