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Ubiquitin–proteasome system, lipid metabolism and DNA damage repair are triggered by antipsychotic medication in human oligodendrocytes: implications in schizophrenia

Schizophrenia is a chronic, severe and disabling psychiatric disorder, whose treatment is based on psychosocial interventions and the use of antipsychotic drugs. While the effects of these drugs are well elucidated in neuronal cells, they are still not so clear in oligodendrocytes, which play a vita...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Seabra, Gabriela, de Almeida, Valéria, Reis-de-Oliveira, Guilherme, Crunfli, Fernanda, Antunes, André Saraiva Leão Marcelo, Martins-de-Souza, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387551/
https://ncbi.nlm.nih.gov/pubmed/32724114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69543-5
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