Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing

The use of primary patient-derived organoids for drug sensitivity and resistance testing could play an important role in precision cancer medicine. We developed expandable ovarian cancer organoids in < 3 weeks; these organoids captured the characteristics of histological cancer subtypes and repli...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nanki, Yoshiko, Chiyoda, Tatsuyuki, Hirasawa, Akira, Ookubo, Aki, Itoh, Manabu, Ueno, Masaru, Akahane, Tomoko, Kameyama, Kaori, Yamagami, Wataru, Kataoka, Fumio, Aoki, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387538/
https://ncbi.nlm.nih.gov/pubmed/32724113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69488-9
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