Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors

Changeux et al. recently suggested that the SARS-CoV-2 spike (S) protein may interact with nicotinic acetylcholine receptors (nAChRs). Such interactions may be involved in pathology and infectivity. Here, we use molecular simulations of validated atomically detailed structures of nAChRs, and of the...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Oliveira, A. Sofia F., Ibarra, Amaurys Avila, Bermudez, Isabel, Casalino, Lorenzo, Gaieb, Zied, Shoemark, Deborah K., Gallagher, Timothy, Sessions, Richard B., Amaro, Rommie E., Mulholland, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386492/
https://ncbi.nlm.nih.gov/pubmed/32743575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.16.206680
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