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Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters through the airways and infects the lungs, causing lethal pulmonary damage in vulnerable patients. This virus contains spike proteins on its envelope that binds to human angiotensin-converting enzyme 2 (hACE2) expressed on the surfa...

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Dettagli Bibliografici
Pubblicato in:bioRxiv
Autori principali: Kim, Jeonghwan, Mukherjee, Anindit, Nelson, Dylan, Jozic, Antony, Sahay, Gaurav
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386491/
https://ncbi.nlm.nih.gov/pubmed/32743574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.24.205583
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