Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation

The zinc-finger protein A20 has crucial physiological functions as a dual inhibitor of nuclear factor-κB (NF-κB) activation and apoptosis in tumor necrosis factor (TNF) receptor 1 signaling pathway. Although the molecular basis for the anti-NF-κB function of A20 has been well elucidated, the anti-ap...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Won, M, Park, KA, Byun, HS, Sohn, K-C, Kim, Y-R, Jeon, J, Hong, JH, Park, J, Seok, JH, Kim, JM, Yoon, W-H, Jang, I-S, Shen, HM, Liu, ZG, Hur, GM
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386326/
https://ncbi.nlm.nih.gov/pubmed/20448643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.47
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