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Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation
The zinc-finger protein A20 has crucial physiological functions as a dual inhibitor of nuclear factor-κB (NF-κB) activation and apoptosis in tumor necrosis factor (TNF) receptor 1 signaling pathway. Although the molecular basis for the anti-NF-κB function of A20 has been well elucidated, the anti-ap...
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| Опубликовано в: : | Cell Death Differ |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7386326/ https://ncbi.nlm.nih.gov/pubmed/20448643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.47 |
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