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Proteomic Study of Fetal Membrane: Inflammation-Triggered Proteolysis of Extracellular Matrix May Present a Pathogenic Pathway for Spontaneous Preterm Birth

INTRODUCTION: Spontaneous preterm birth (sPTB), which predominantly presents as spontaneous preterm labor (sPTL) or prelabor premature rupture of membranes (PPROM), is a syndrome that accounts for 5–10% of live births annually. The long-term morbidity in surviving preterm infants is significantly hi...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Pan, Jing, Tian, Xiujuan, Huang, Honglei, Zhong, Nanbert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386131/
https://ncbi.nlm.nih.gov/pubmed/32792973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00800
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