Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences

BACKGROUND: The social motivational theory of autism spectrum disorder (ASD) focuses on social anhedonia as key causal feature of the impaired peer relationships that characterize ASD patients. ASD prevalence is higher in boys, but increasing evidence suggests underdiagnosis and undertreatment in gi...

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Veröffentlicht in:Mol Autism
Hauptverfasser: Scheggi, Simona, Guzzi, Francesca, Braccagni, Giulia, De Montis, Maria Graziella, Parenti, Marco, Gambarana, Carla
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385875/
https://ncbi.nlm.nih.gov/pubmed/32718349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00358-x
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