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Bovine breed-specific augmented reference graphs facilitate accurate sequence read mapping and unbiased variant discovery
BACKGROUND: The current bovine genomic reference sequence was assembled from a Hereford cow. The resulting linear assembly lacks diversity because it does not contain allelic variation, a drawback of linear references that causes reference allele bias. High nucleotide diversity and the separation of...
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| Publicado no: | Genome Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385871/ https://ncbi.nlm.nih.gov/pubmed/32718320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02105-0 |
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