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Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd

Mfd couples transcription to nucleotide excision repair, and acts on RNA polymerases when elongation is impeded. Depending on impediment severity, this action results in either transcription termination or elongation rescue, which rely on ATP-dependent Mfd translocation on DNA. Due to its role in an...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Brugger, Christiane, Zhang, Cheng, Suhanovsky, Margaret M., Kim, David D., Sinclair, Amy N., Lyumkis, Dmitry, Deaconescu, Alexandra M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385628/
https://ncbi.nlm.nih.gov/pubmed/32719356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17457-1
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