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Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions

Antibody drugs play an important role in biopharmaceuticals, because of the specificity for target biomolecules and reduction of side effects. Thus, separation and analysis techniques for these antibody drugs have increased in importance. In the present study, we develop functional chromatography ma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nagase, Kenichi, Ishii, Saki, Ikeda, Koji, Yamada, Sota, Ichikawa, Daiju, Akimoto, Aya Mizutani, Hattori, Yutaka, Kanazawa, Hideko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385495/
https://ncbi.nlm.nih.gov/pubmed/32719404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68707-7
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