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GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice
Stress can lead to obesity and metabolic dysfunction, but the underlying mechanisms are unclear. Here we identify GADD45α, a stress-inducible histone folding protein, as a potential regulator for brown adipose tissue biogenesis. Unbiased transcriptomics data indicate a positive correlation between a...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385159/ https://ncbi.nlm.nih.gov/pubmed/32719383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02802-5 |
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