Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma

Glucocorticoids (GC) are a controversial yet commonly used intervention in the clinical management of acute inflammatory conditions, including sepsis or traumatic injury. In the context of major trauma such as surgery, concerns have been raised regarding adverse effects from GC, thereby necessitatin...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Ganio, Edward A., Stanley, Natalie, Lindberg-Larsen, Viktoria, Einhaus, Jakob, Tsai, Amy S., Verdonk, Franck, Culos, Anthony, Gahemi, Sajjad, Rumer, Kristen K., Stelzer, Ina A., Gaudilliere, Dyani, Tsai, Eileen, Fallahzadeh, Ramin, Choisy, Benjamin, Kehlet, Henrik, Aghaeepour, Nima, Angst, Martin S., Gaudilliere, Brice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385146/
https://ncbi.nlm.nih.gov/pubmed/32719355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17565-y
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