TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis

TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is implicated in myeloid malignancies with deletion of chromosome 5q. Employing a combination of proteomic and genetic approaches, we find that TIFAB regulates ubiquitin-specific peptidase 15 (USP15) ubiquitin hydrolase activity. E...

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Publicado no:Cell Rep
Main Authors: Niederkorn, Madeline, Hueneman, Kathleen, Choi, Kwangmin, Varney, Melinda E., Romano, Laurel, Pujato, Mario A., Greis, Kenneth D., Inoue, Jun-ichiro, Meetei, Ruhikanta, Starczynowski, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384867/
https://ncbi.nlm.nih.gov/pubmed/32101751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.093
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