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Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics
BACKGROUND: Single-cell RNA sequencing is a powerful tool for characterizing cellular heterogeneity in gene expression. However, high variability and a large number of zero counts present challenges for analysis and interpretation. There is substantial controversy over the origins and proper treatme...
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| Publicat a: | Genome Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384222/ https://ncbi.nlm.nih.gov/pubmed/32718323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02103-2 |
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