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Randomised clinical trial: linaclotide vs placebo—a study of bi‐directional gut and brain axis
BACKGROUND: Linaclotide, a guanylate cyclase C agonist relieves irritable bowel syndrome with predominant constipation (IBS‐C) symptoms, but how it improves pain in humans is unknown. AIMS: To investigate the effects of linaclotide and placebo on the afferent and efferent gut‐brain‐gut signalling in...
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| Publicado no: | Aliment Pharmacol Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384154/ https://ncbi.nlm.nih.gov/pubmed/32406112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.15772 |
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