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CD8(+) T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization

Pregnancy necessitates physiological exposure, and often re-exposure, to foreign fetal alloantigens. The consequences after pregnancy are highly varied, with evidence of both alloimmunization and expanded tolerance phenotypes. We show that pregnancy primes the accumulation of fetal-specific maternal...

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Pubblicato in:Cell Rep
Autori principali: Kinder, Jeremy M., Turner, Lucien H., Stelzer, Ina A., Miller-Handley, Hilary, Burg, Ashley, Shao, Tzu-Yu, Pham, Giang, Way, Sing Sing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383938/
https://ncbi.nlm.nih.gov/pubmed/32579916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107784
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