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Purifying stem cell‐derived red blood cells: a high‐throughput label‐free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration

Cell‐based therapeutics, such as in vitro manufactured red blood cells (mRBCs), are different to traditional biopharmaceutical products (the final product being the cells themselves as opposed to biological molecules such as proteins) and that presents a challenge of developing new robust and econom...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Guzniczak, Ewa, Otto, Oliver, Whyte, Graeme, Chandra, Tamir, Robertson, Neil A., Willoughby, Nik, Jimenez, Melanie, Bridle, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383897/
https://ncbi.nlm.nih.gov/pubmed/32100873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27319
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