Label‐Free Nanoimaging of Neuromelanin in the Brain by Soft X‐ray Spectromicroscopy

A hallmark of Parkinson's disease is the death of neuromelanin‐pigmented neurons, but the role of neuromelanin is unclear. The in situ characterization of neuromelanin remains dependent on detectable pigmentation, rather than direct quantification of neuromelanin. We show that direct, label‐fre...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Brooks, Jake, Everett, James, Lermyte, Frederik, Tjhin, Vindy Tjendana, Banerjee, Samya, O'Connor, Peter B., Morris, Christopher M., Sadler, Peter J., Telling, Neil D., Collingwood, Joanna F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383895/
https://ncbi.nlm.nih.gov/pubmed/32227670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202000239
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