Acute Negative Allosteric Modulation of M(5) Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with no effect on Antinociception

Opioid Use Disorder (OUD) is a debilitating neuropsychiatric condition characterized by compulsive opioid use, dependence, and repeated relapse after periods of abstinence. Given the high risk of developing OUD following prescription opioid use, the continued need for opioid-induced analgesia, and t...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Gould, Robert W., Gunter, Barak W., Bubser, Michael, Matthews, Robert T., Teal, Laura B., Ragland, Madeline G., Bridges, Thomas M., Garrison, Aaron T., Winder, Danny G., Lindsley, Craig W., Jones, Carrie K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383364/
https://ncbi.nlm.nih.gov/pubmed/31268669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00274
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