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MCH Neurons Regulate Permeability of the Median Eminence Barrier

Melanin-concentrating hormone (MCH)-expressing neurons are key regulators of energy and glucose homeostasis. Here, we demonstrate that they provide dense projections to the median eminence (ME) in close proximity to tanycytes and fenestrated vessels. Chemogenetic activation of MCH neurons as well as...

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Pubblicato in:Neuron
Autori principali: Jiang, Hong, Gallet, Sarah, Klemm, Paul, Scholl, Pia, Folz-Donahue, Kat, Altmüller, Janine, Alber, Jens, Heilinger, Christian, Kukat, Christian, Loyens, Anne, Müller-Fielitz, Helge, Sundaram, Sivaraj, Schwaninger, Markus, Prevot, Vincent, Brüning, Jens C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383232/
https://ncbi.nlm.nih.gov/pubmed/32407670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.04.020
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