Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR)

PURPOSE: Cervical cancer metastasis results in poor prognosis and increased mortality, which is not separated from inflammatory reactions accumulated by prostaglandin E2 (PGE2). As a specific G-protein coupled PGE2 receptor, EP3 is demonstrated as a negative prognosticator of cervical malignancy. No...

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Pubblicato in:J Cancer Res Clin Oncol
Autori principali: Ye, Yao, Peng, Lin, Vattai, Aurelia, Deuster, Eileen, Kuhn, Christina, Dannecker, Christian, Mahner, Sven, Jeschke, Udo, von Schönfeldt, Viktoria, Heidegger, Helene H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Original Article – Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382663/
https://ncbi.nlm.nih.gov/pubmed/32488496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-020-03272-0
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