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The cholinesterase inhibitor donepezil has antidepressant-like properties in the mouse forced swim test

Finding new antidepressant agents is of high clinical priority given that many cases of major depressive disorder (MDD) do not respond to conventional monoaminergic antidepressants such as the selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and monoamine oxidase inhibitor...

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Publicat a:Transl Psychiatry
Autors principals: Fitzgerald, Paul J., Hale, Pho J., Ghimire, Anjesh, Watson, Brendon O.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382650/
https://ncbi.nlm.nih.gov/pubmed/32712627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00928-w
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