Obesity reduces the real-world effectiveness of cytokine-targeted but not cell-targeted disease-modifying agents in rheumatoid arthritis

OBJECTIVES: The effectiveness of TNF inhibitors in RA has been shown to be affected by obesity. No such effect has been found for abatacept and rituximab, while for tocilizumab results are ambiguous. Additionally, it remains unresolved whether sex is an effect modifier for obesity. We investigated t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Rheumatology (Oxford)
Hauptverfasser: Schäfer, Martin, Meißner, Yvette, Kekow, Jörn, Berger, Sylvia, Remstedt, Sven, Manger, Bernhard, Listing, Joachim, Strangfeld, Anja, Zink, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Clinical Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382601/
https://ncbi.nlm.nih.gov/pubmed/31745566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez535
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